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Activated Microglia Disrupt the Blood-Brain Barrier and Induce Chemokines and Cytokines in a Rat in vitro Model

Severe neuroinflammation is associated with blood brain barrier (BBB) disruption in CNS diseases. Although microglial activation and the subsequent changes in cytokine/chemokine (C/C) concentrations are thought to be key steps in the development of neuroinflammation, little data are available concer...

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Detalles Bibliográficos
Autores principales: Shigemoto-Mogami, Yukari, Hoshikawa, Kazue, Sato, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300509/
https://www.ncbi.nlm.nih.gov/pubmed/30618641
http://dx.doi.org/10.3389/fncel.2018.00494