Cargando…
Activated Microglia Disrupt the Blood-Brain Barrier and Induce Chemokines and Cytokines in a Rat in vitro Model
Severe neuroinflammation is associated with blood brain barrier (BBB) disruption in CNS diseases. Although microglial activation and the subsequent changes in cytokine/chemokine (C/C) concentrations are thought to be key steps in the development of neuroinflammation, little data are available concer...
Autores principales: | Shigemoto-Mogami, Yukari, Hoshikawa, Kazue, Sato, Kaoru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300509/ https://www.ncbi.nlm.nih.gov/pubmed/30618641 http://dx.doi.org/10.3389/fncel.2018.00494 |
Ejemplares similares
-
Glypican 6 Enhances N-Methyl-D-Aspartate Receptor Function in Human-Induced Pluripotent Stem Cell-Derived Neurons
por: Sato, Kaoru, et al.
Publicado: (2016) -
Usefulness of a humanized tricellular static transwell blood–brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system
por: Nakayama-Kitamura, Kimiko, et al.
Publicado: (2023) -
Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays
por: Piantino, Marie, et al.
Publicado: (2022) -
Brain microvascular endothelial cells derived from human induced pluripotent stem cells as in vitro model for assessing blood-brain barrier transferrin receptor-mediated transcytosis
por: Piantino, Marie, et al.
Publicado: (2022) -
Blood-Brain Barrier Disruption Induced Cognitive Impairment Is Associated With Increase of Inflammatory Cytokine
por: Geng, Jieli, et al.
Publicado: (2018)