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Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V

In order to preserve genomic stability, cells rely on various repair pathways for removing DNA damage. The mechanisms how enzymes scan DNA and recognize their target sites are incompletely understood. Here, by using high-localization precision microscopy along with 133 Hz high sampling rate, we have...

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Detalles Bibliográficos
Autores principales: Ahmadi, Arash, Rosnes, Ida, Blicher, Pernille, Diekmann, Robin, Schüttpelz, Mark, Glette, Kyrre, Tørresen, Jim, Bjørås, Magnar, Dalhus, Bjørn, Rowe, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300609/
https://www.ncbi.nlm.nih.gov/pubmed/30568191
http://dx.doi.org/10.1038/s41467-018-07797-4