Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy

Development of resistance to chemotherapy is a major obstacle in extending the survival of patients with cancer. Although originally defined as an immune checkpoint molecule, B7-H1 (also named as PD-L1 or CD274) was found to play a role in cancer chemoresistance; however, the underlying mechanism of...

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Detalles Bibliográficos
Autores principales: Wu, Xiaosheng, Li, Yanli, Liu, Xin, Chen, Chunhua, Harrington, Susan M., Cao, Siyu, Xie, Tiancheng, Pham, Tu, Mansfield, Aaron S., Yan, Yiyi, Kwon, Eugene D., Wang, Liewei, Ling, Kun, Dong, Haidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300616/
https://www.ncbi.nlm.nih.gov/pubmed/30603685
http://dx.doi.org/10.1016/j.heliyon.2018.e01039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300616/
https://www.ncbi.nlm.nih.gov/pubmed/30603685
http://dx.doi.org/10.1016/j.heliyon.2018.e01039

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