Detection of Innate and Artificial Mitochondrial DNA Heteroplasmy by Massively Parallel Sequencing: Considerations for Analysis

BACKGROUND: Mitochondrial heteroplasmy, the co-existence of different mitochondrial polymorphisms within an individual, has various forensic and clinical implications. But there is still no guideline on the application of massively parallel sequencing (MPS) in heteroplasmy detection. We present here...

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Detalles Bibliográficos
Autores principales: Kim, Moon-Young, Cho, Sohee, Lee, Ji Hyun, Seo, Hee Jin, Lee, Soong Deok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300661/
https://www.ncbi.nlm.nih.gov/pubmed/30584415
http://dx.doi.org/10.3346/jkms.2018.33.e337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300661/
https://www.ncbi.nlm.nih.gov/pubmed/30584415
http://dx.doi.org/10.3346/jkms.2018.33.e337

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