High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

Genome-wide epigenomic maps have revealed millions of putative enhancers and promoters, but experimental validation of their function and high-resolution dissection of their driver nucleotides remain limited. Here, we present HiDRA (High-resolution Dissection of Regulatory Activity), a combined expe...

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Detalles Bibliográficos
Autores principales: Wang, Xinchen, He, Liang, Goggin, Sarah M., Saadat, Alham, Wang, Li, Sinnott-Armstrong, Nasa, Claussnitzer, Melina, Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300699/
https://www.ncbi.nlm.nih.gov/pubmed/30568279
http://dx.doi.org/10.1038/s41467-018-07746-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300699/
https://www.ncbi.nlm.nih.gov/pubmed/30568279
http://dx.doi.org/10.1038/s41467-018-07746-1

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