Photolysis of a Caged, Fast-Equilibrating Glutamate Receptor Antagonist, MNI-Caged γ-D-Glutamyl-Glycine, to Investigate Transmitter Dynamics and Receptor Properties at Glutamatergic Synapses

Fast uncaging of low affinity competitive receptor antagonists can in principle measure the timing and concentration dependence of transmitter action at receptors during synaptic transmission. Here, we describe the development, synthesis and characterization of MNI-caged γ-D-glutamyl-glycine (γ-DGG)...

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Detalles Bibliográficos
Autores principales: Palma-Cerda, Francisco, Papageorgiou, George, Barbour, Boris, Auger, Céline, Ogden, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300705/
https://www.ncbi.nlm.nih.gov/pubmed/30618624
http://dx.doi.org/10.3389/fncel.2018.00465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300705/
https://www.ncbi.nlm.nih.gov/pubmed/30618624
http://dx.doi.org/10.3389/fncel.2018.00465

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