Exosomes derived from siRNA against GRP78 modified bone-marrow-derived mesenchymal stem cells suppress Sorafenib resistance in hepatocellular carcinoma

BACKGROUND: Sorafenib is an effective clinical drug in therapy of hepatocellular carcinoma, having led to improved prognosis in hepatocellular carcinoma patients. However acquired resistance is still being encountered. So, it is urgently to develop alternative strategies to overcome drug resistance....

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Detalles Bibliográficos
Autores principales: Li, Hongdan, Yang, Cheng, Shi, Yijie, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300915/
https://www.ncbi.nlm.nih.gov/pubmed/30572882
http://dx.doi.org/10.1186/s12951-018-0429-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300915/
https://www.ncbi.nlm.nih.gov/pubmed/30572882
http://dx.doi.org/10.1186/s12951-018-0429-z

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