Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

The mammary gland consists of cells with gene expression patterns reflecting their cellular origins, function, and spatiotemporal context. However, knowledge of developmental kinetics and mechanisms of lineage specification is lacking. We address this significant knowledge gap by generating a single...

Descripción completa

Detalles Bibliográficos
Autores principales: Giraddi, Rajshekhar R., Chung, Chi-Yeh, Heinz, Richard E., Balcioglu, Ozlen, Novotny, Mark, Trejo, Christy L., Dravis, Christopher, Hagos, Berhane M., Mehrabad, Elnaz Mirzaei, Rodewald, Luo Wei, Hwang, Jae Y., Fan, Cheng, Lasken, Roger, Varley, Katherine E., Perou, Charles M., Wahl, Geoffrey M., Spike, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301014/
https://www.ncbi.nlm.nih.gov/pubmed/30089273
http://dx.doi.org/10.1016/j.celrep.2018.07.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301014/
https://www.ncbi.nlm.nih.gov/pubmed/30089273
http://dx.doi.org/10.1016/j.celrep.2018.07.025

Ejemplares similares