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Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats

PURPOSE: This study explored whether Jian-Pi-Zhi-Dong-Decoction (JPZDD) could regulate the metabolism of glutamate (GLU) and its transporters in the striatum to exert anti-tics effects in Tourette syndrome (TS) rats. MATERIALS AND METHODS: We randomly assigned 56 Sprague Dawley rats into four groups...

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Detalles Bibliográficos
Autores principales: Yu, Wenjing, Shi, Xiaowei, Cui, Xia, Niu, Yan, Zhang, Wen, Bai, Xue, Wang, Qian, Hu, Lijun, Wang, Sumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301307/
https://www.ncbi.nlm.nih.gov/pubmed/30587990
http://dx.doi.org/10.2147/NDT.S185169