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Regulation of gastric smooth muscle contraction via Ca(2+)-dependent and Ca(2+)-independent actin polymerization

In gastrointestinal smooth muscle, acetylcholine induced muscle contraction is biphasic, initial peak followed by sustained contraction. Contraction is regulated by phosphorylation of 20 kDa myosin light chain (MLC) at Ser(19), interaction of actin and myosin, and actin polymerization. The present s...

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Detalles Bibliográficos
Autores principales: Mahavadi, Sunila, Nalli, Ancy D., Wang, Hongxia, Kendig, Derek M., Crowe, Molly S., Lyall, Vijay, Grider, John R., Murthy, Karnam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301582/
https://www.ncbi.nlm.nih.gov/pubmed/30571746
http://dx.doi.org/10.1371/journal.pone.0209359