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Investigating epigenetic effects of activation-induced deaminase in chronic lymphocytic leukemia

Activation induced deaminase (AID) has two distinct and well defined roles, both relying on its deoxycytidine (dC) deaminating function: one as a DNA mutator and another in DNA demethylation. In chronic lymphocytic leukemia (CLL), AID was previously shown to be an independent negative prognostic fac...

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Detalles Bibliográficos
Autores principales: Schubert, Maria, Hackl, Hubert, Gassner, Franz Josef, Greil, Richard, Geisberger, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301619/
https://www.ncbi.nlm.nih.gov/pubmed/30571766
http://dx.doi.org/10.1371/journal.pone.0208753