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Investigating epigenetic effects of activation-induced deaminase in chronic lymphocytic leukemia
Activation induced deaminase (AID) has two distinct and well defined roles, both relying on its deoxycytidine (dC) deaminating function: one as a DNA mutator and another in DNA demethylation. In chronic lymphocytic leukemia (CLL), AID was previously shown to be an independent negative prognostic fac...
Autores principales: | Schubert, Maria, Hackl, Hubert, Gassner, Franz Josef, Greil, Richard, Geisberger, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301619/ https://www.ncbi.nlm.nih.gov/pubmed/30571766 http://dx.doi.org/10.1371/journal.pone.0208753 |
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