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Synergistic enhancement of production of proinflammatory cytokines of human peripheral blood monocytes by anti-Sm and anti-RNP antibodies

The present study was performed to elucidate the roles of serum anti-Sm antibodies in the pathogenesis of systemic lupus erythematosus (SLE). Highly purified peripheral blood monocytes obtained from healthy donors were cultured in the presence of monoclonal anti-Sm antibody (anti-Sm mAb), monoclonal...

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Detalles Bibliográficos
Autores principales: Matsueda, Yu, Arinuma, Yoshiyuki, Nagai, Tatsuo, Hirohata, Shunsei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301657/
https://www.ncbi.nlm.nih.gov/pubmed/30571738
http://dx.doi.org/10.1371/journal.pone.0209282