Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC

Scrapie is a naturally occurring transmissible spongiform encephalopathy of sheep and goats. This fatal neurodegenerative disease is caused by misfolding of the cellular prion protein to pathogenic β-rich conformers (PrP(Sc)) that accumulate in higher order structures of the brain and other tissues....

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Detalles Bibliográficos
Autores principales: Hwang, Soyoun, Greenlee, Justin J., Vance, Natalie M., Nicholson, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301698/
https://www.ncbi.nlm.nih.gov/pubmed/30571737
http://dx.doi.org/10.1371/journal.pone.0209106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301698/
https://www.ncbi.nlm.nih.gov/pubmed/30571737
http://dx.doi.org/10.1371/journal.pone.0209106

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