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Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC
Scrapie is a naturally occurring transmissible spongiform encephalopathy of sheep and goats. This fatal neurodegenerative disease is caused by misfolding of the cellular prion protein to pathogenic β-rich conformers (PrP(Sc)) that accumulate in higher order structures of the brain and other tissues....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301698/ https://www.ncbi.nlm.nih.gov/pubmed/30571737 http://dx.doi.org/10.1371/journal.pone.0209106 |