Cargando…

Enzymatic and non-enzymatic pathways of kynurenines' dimerization: the molecular factors for oxidative stress development

Kynurenines, the products of tryptophan oxidative degradation, are involved in multiple neuropathologies, such as Huntington's chorea, Parkinson's disease, senile dementia, etc. The major cause for hydroxykynurenines's neurotoxicity is the oxidative stress induced by the reactive oxyg...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuravlev, Aleksandr V., Vetrovoy, Oleg V., Savvateeva-Popova, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301705/
https://www.ncbi.nlm.nih.gov/pubmed/30532237
http://dx.doi.org/10.1371/journal.pcbi.1006672