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RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation
In Drosophila melanogaster, the male-specific lethal (MSL) complex plays a key role in dosage compensation by stimulating expression of male X-chromosome genes. It consists of MSL proteins and two long noncoding RNAs, roX1 and roX2, that are required for spreading of the complex on the chromosome an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301720/ https://www.ncbi.nlm.nih.gov/pubmed/30532158 http://dx.doi.org/10.1371/journal.pgen.1007842 |