Voltage-dependent dynamics of the BK channel cytosolic gating ring are coupled to the membrane-embedded voltage sensor

In humans, large conductance voltage- and calcium-dependent potassium (BK) channels are regulated allosterically by transmembrane voltage and intracellular Ca(2+). Divalent cation binding sites reside within the gating ring formed by two Regulator of Conductance of Potassium (RCK) domains per subuni...

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Detalles Bibliográficos
Autores principales: Miranda, Pablo, Holmgren, Miguel, Giraldez, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301790/
https://www.ncbi.nlm.nih.gov/pubmed/30526860
http://dx.doi.org/10.7554/eLife.40664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301790/
https://www.ncbi.nlm.nih.gov/pubmed/30526860
http://dx.doi.org/10.7554/eLife.40664

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