Multi-protein bridging factor 1(Mbf1), Rps3 and Asc1 prevent stalled ribosomes from frameshifting

Reading frame maintenance is critical for accurate translation. We show that the conserved eukaryotic/archaeal protein Mbf1 acts with ribosomal proteins Rps3/uS3 and eukaryotic Asc1/RACK1 to prevent frameshifting at inhibitory CGA-CGA codon pairs in the yeast Saccharomyces cerevisiae. Mutations in R...

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Detalles Bibliográficos
Autores principales: Wang, Jiyu, Zhou, Jie, Yang, Qidi, Grayhack, Elizabeth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301793/
https://www.ncbi.nlm.nih.gov/pubmed/30465652
http://dx.doi.org/10.7554/eLife.39637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301793/
https://www.ncbi.nlm.nih.gov/pubmed/30465652
http://dx.doi.org/10.7554/eLife.39637

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