A high molar activity (18)F-labeled TAK-875 derivative for PET imaging of pancreatic β-cells

BACKGROUND: The free-fatty acid receptor-1 (FFA-1) is expressed by β-cells and is a promising target for molecular imaging of functional β-cell mass. Recently, the ((3-[(18)F]fluoropropyl)sulfonyl)propoxy-derivative of the high-affinity FFA-1 agonist TAK-875 ([(18)F]7) was reported. Here we describe...

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Detalles Bibliográficos
Autores principales: Dornan, Mark H., Petrenyov, Daniil, Simard, José-Mathieu, Aliaga, Antonio, Xiong, Guoming, Ghislain, Julien, Bedell, Barry, Poitout, Vincent, DaSilva, Jean N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301904/
http://dx.doi.org/10.1186/s41181-018-0051-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301904/
http://dx.doi.org/10.1186/s41181-018-0051-2

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