Cargando…

Mathematical-model-guided development of full-thickness epidermal equivalent

Epidermal equivalents prepared with passaged keratinocytes are typically 10–20 μm thick, whereas intact human epidermis is up to 100 μm thick. Our established mathematical model of epidermal homeostasis predicted that the undulatory pattern of the papillary layer beneath the epidermis is a key deter...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumamoto, Junichi, Nakanishi, Shinobu, Makita, Mio, Uesaka, Masaaki, Yasugahira, Yusuke, Kobayashi, Yasuaki, Nagayama, Masaharu, Denda, Sumiko, Denda, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301960/
https://www.ncbi.nlm.nih.gov/pubmed/30573749
http://dx.doi.org/10.1038/s41598-018-36647-y