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Modulation of benzylisoquinoline alkaloid biosynthesis by overexpression berberine bridge enzyme in Macleaya cordata

Macleaya cordata produces a variety of benzylisoquinoline alkaloids (BIAs), such as sanguinarine, protopine, and berberine, which are potential anticancer drugs and natural growth promoters. The genes encoding the berberine bridge enzyme (BBE) were isolated from M. cordata and Papaver somniferum, an...

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Detalles Bibliográficos
Autores principales: Huang, Peng, Liu, Wei, Xu, Min, Jiang, Ruolan, Xia, Liqiong, Wang, Peng, Li, Han, Tang, Zhaoshan, Zheng, Qiyin, Zeng, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301961/
https://www.ncbi.nlm.nih.gov/pubmed/30573738
http://dx.doi.org/10.1038/s41598-018-36211-8