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Extra-mitochondrial Cu/Zn superoxide dismutase (Sod1) is dispensable for protection against oxidative stress but mediates peroxide signaling in Saccharomyces cerevisiae

Cu/Zn Superoxide Dismutase (Sod1) is a highly conserved and abundant metalloenzyme that catalyzes the disproportionation of superoxide radicals into hydrogen peroxide and molecular oxygen. As a consequence, Sod1 serves dual roles in oxidative stress protection and redox signaling by both scavenging...

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Detalles Bibliográficos
Autores principales: Montllor-Albalate, Claudia, Colin, Alyson E., Chandrasekharan, Bindu, Bolaji, Naimah, Andersen, Joshua L., Wayne Outten, F., Reddi, Amit R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302037/
https://www.ncbi.nlm.nih.gov/pubmed/30576923
http://dx.doi.org/10.1016/j.redox.2018.11.022