Cargando…

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular defense mechanisms as well as physiological functions, and intracellular signaling. However, excessive ROS generation (endogenous and exogenous) can create a state of redox imbalance leading to cellular and tiss...

Descripción completa

Detalles Bibliográficos
Autores principales: Sivandzade, Farzane, Prasad, Shikha, Bhalerao, Aditya, Cucullo, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302038/
https://www.ncbi.nlm.nih.gov/pubmed/30576920
http://dx.doi.org/10.1016/j.redox.2018.11.017