Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures

Background: The role of GABA-B neurotransmission in addiction has recently received increased attention, with clinical trials indicating that baclofen, a GABA-B receptor agonist, may reduce alcohol consumption, craving and promote abstinence. However, the optimal dose to treat alcohol dependence is...

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Detalles Bibliográficos
Autores principales: Durant, Claire F., Paterson, Louise M., Turton, Sam, Wilson, Susan J., Myers, James F. M., Muthukumaraswamy, Suresh, Venkataraman, Ashwin, Mick, Inge, Paterson, Susan, Jones, Tessa, Nahar, Limon K., Cordero, Rosa E., Nutt, David J., Lingford-Hughes, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302106/
https://www.ncbi.nlm.nih.gov/pubmed/30618857
http://dx.doi.org/10.3389/fpsyt.2018.00664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302106/
https://www.ncbi.nlm.nih.gov/pubmed/30618857
http://dx.doi.org/10.3389/fpsyt.2018.00664

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