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Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages

Dysregulation of cholesterol metabolism represents one of the major risk factors for atherosclerotic cardiovascular disease (CVD). Oxidized cholesterol esters (oxCE) in low-density lipoprotein (LDL) have been implicated in CVD but the underlying mechanisms remain poorly defined. We use a targeted li...

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Detalles Bibliográficos
Autores principales: Guo, Shuyuan, Lu, Jianhong, Zhuo, Yujuan, Xiao, Mengqing, Xue, Xinli, Zhong, Shanshan, Shen, Xia, Yin, Chunzhao, Li, Luxiao, Chen, Qun, Zhu, Mingjiang, Chen, Buxing, Zhao, Mingming, Zheng, Lemin, Tao, Yongzhen, Yin, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302155/
https://www.ncbi.nlm.nih.gov/pubmed/30576926
http://dx.doi.org/10.1016/j.redox.2018.101069