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Long non-coding RNA H19 regulates endothelial cell aging via inhibition of STAT3 signalling

AIMS: Long non-coding RNAs (lncRNAs) have been shown to regulate numerous processes in the human genome, but the function of these transcripts in vascular aging is largely unknown. We aim to characterize the expression of lncRNAs in endothelial aging and analyse the function of the highly conserved...

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Detalles Bibliográficos
Autores principales: Hofmann, Patrick, Sommer, Janina, Theodorou, Kosta, Kirchhof, Luisa, Fischer, Ariane, Li, Yuhuang, Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Dimmeler, Stefanie, Boon, Reinier A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302267/
https://www.ncbi.nlm.nih.gov/pubmed/30107531
http://dx.doi.org/10.1093/cvr/cvy206