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Levofloxacin versus placebo for the prevention of tuberculosis disease in child contacts of multidrug-resistant tuberculosis: study protocol for a phase III cluster randomised controlled trial (TB-CHAMP)

BACKGROUND: Multidrug-resistant (MDR) tuberculosis (TB) presents a challenge for global TB control. Treating individuals with MDR-TB infection to prevent progression to disease could be an effective public health strategy. Young children are at high risk of developing TB disease following infection...

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Detalles Bibliográficos
Autores principales: Seddon, James A., Garcia-Prats, Anthony J., Purchase, Susan E., Osman, Muhammad, Demers, Anne-Marie, Hoddinott, Graeme, Crook, Angela M., Owen-Powell, Ellen, Thomason, Margaret J., Turkova, Anna, Gibb, Diana M., Fairlie, Lee, Martinson, Neil, Schaaf, H. Simon, Hesseling, Anneke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302301/
https://www.ncbi.nlm.nih.gov/pubmed/30572905
http://dx.doi.org/10.1186/s13063-018-3070-0