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Anti-α4β1 Integrin Antibodies Attenuated Brain Inflammatory Changes in a Mouse Model of Alzheimer’s Disease

BACKGROUND: Alzheimer’s disease (AD) is associated with age-associated central nervous sys-tem degeneration and dementia. This decline in the function correlates with deposition of Aβ peptide con-taining plaques and associated reactive gliosis. The inflammatory phenotype of microglia, in particular,...

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Detalles Bibliográficos
Autores principales: Manocha, Gunjan, Ghatak, Atreyi, Puig, Kendra, Combs, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302348/
https://www.ncbi.nlm.nih.gov/pubmed/30068274
http://dx.doi.org/10.2174/1567205015666180801111033