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Anti-α4β1 Integrin Antibodies Attenuated Brain Inflammatory Changes in a Mouse Model of Alzheimer’s Disease
BACKGROUND: Alzheimer’s disease (AD) is associated with age-associated central nervous sys-tem degeneration and dementia. This decline in the function correlates with deposition of Aβ peptide con-taining plaques and associated reactive gliosis. The inflammatory phenotype of microglia, in particular,...
Autores principales: | Manocha, Gunjan, Ghatak, Atreyi, Puig, Kendra, Combs, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302348/ https://www.ncbi.nlm.nih.gov/pubmed/30068274 http://dx.doi.org/10.2174/1567205015666180801111033 |
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