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Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis

BACKGROUND: A hallmark of atherosclerosis is its complex pathogenesis, which is dependent on altered cholesterol metabolism and inflammation. Both arms of pathogenesis involve myeloid cells. Monocytes migrating into the arterial walls interact with modified low-density lipoprotein (LDL) parti-cles,...

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Detalles Bibliográficos
Autores principales: Orekhov, Alexander N., Oishi, Yumiko, Nikiforov, Nikita G., Zhelankin, Andrey V., Dubrovsky, Larisa, Sobenin, Igor A., Kel, Alexander, Stelmashenko, Daria, Makeev, Vsevolod J., Foxx, Kathy, Jin, Xueting, Kruth, Howard S., Bukrinsky, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302360/
https://www.ncbi.nlm.nih.gov/pubmed/30205792
http://dx.doi.org/10.2174/1381612824666180911120039