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Modified LDL Particles Activate Inflammatory Pathways in Monocyte-derived Macrophages: Transcriptome Analysis
BACKGROUND: A hallmark of atherosclerosis is its complex pathogenesis, which is dependent on altered cholesterol metabolism and inflammation. Both arms of pathogenesis involve myeloid cells. Monocytes migrating into the arterial walls interact with modified low-density lipoprotein (LDL) parti-cles,...
Autores principales: | Orekhov, Alexander N., Oishi, Yumiko, Nikiforov, Nikita G., Zhelankin, Andrey V., Dubrovsky, Larisa, Sobenin, Igor A., Kel, Alexander, Stelmashenko, Daria, Makeev, Vsevolod J., Foxx, Kathy, Jin, Xueting, Kruth, Howard S., Bukrinsky, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302360/ https://www.ncbi.nlm.nih.gov/pubmed/30205792 http://dx.doi.org/10.2174/1381612824666180911120039 |
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