An experimental design framework for Markovian gene regulatory networks under stationary control policy

BACKGROUND: A fundamental problem for translational genomics is to find optimal therapies based on gene regulatory intervention. Dynamic intervention involves a control policy that optimally reduces a cost function based on phenotype by externally altering the state of the network over time. When a...

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Detalles Bibliográficos
Autores principales: Dehghannasiri, Roozbeh, Shahrokh Esfahani, Mohammad, Dougherty, Edward R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302376/
https://www.ncbi.nlm.nih.gov/pubmed/30577732
http://dx.doi.org/10.1186/s12918-018-0649-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302376/
https://www.ncbi.nlm.nih.gov/pubmed/30577732
http://dx.doi.org/10.1186/s12918-018-0649-8

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