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An experimental design framework for Markovian gene regulatory networks under stationary control policy

BACKGROUND: A fundamental problem for translational genomics is to find optimal therapies based on gene regulatory intervention. Dynamic intervention involves a control policy that optimally reduces a cost function based on phenotype by externally altering the state of the network over time. When a...

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Detalles Bibliográficos
Autores principales:	Dehghannasiri, Roozbeh, Shahrokh Esfahani, Mohammad, Dougherty, Edward R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302376/ https://www.ncbi.nlm.nih.gov/pubmed/30577732 http://dx.doi.org/10.1186/s12918-018-0649-8

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