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NGmerge: merging paired-end reads via novel empirically-derived models of sequencing errors
BACKGROUND: Advances in Illumina DNA sequencing technology have produced longer paired-end reads that increasingly have sequence overlaps. These reads can be merged into a single read that spans the full length of the original DNA fragment, allowing for error correction and accurate determination of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302405/ https://www.ncbi.nlm.nih.gov/pubmed/30572828 http://dx.doi.org/10.1186/s12859-018-2579-2 |