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NGmerge: merging paired-end reads via novel empirically-derived models of sequencing errors

BACKGROUND: Advances in Illumina DNA sequencing technology have produced longer paired-end reads that increasingly have sequence overlaps. These reads can be merged into a single read that spans the full length of the original DNA fragment, allowing for error correction and accurate determination of...

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Detalles Bibliográficos
Autor principal: Gaspar, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302405/
https://www.ncbi.nlm.nih.gov/pubmed/30572828
http://dx.doi.org/10.1186/s12859-018-2579-2

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