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Developing Gram-negative bacteria for the secretion of heterologous proteins

Gram-negative bacteria are attractive hosts for recombinant protein production because they are fast growing, easy to manipulate, and genetically stable in large cultures. However, the utility of these microbes would expand if they also could secrete the product at commercial scales. Secretion of bi...

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Detalles Bibliográficos
Autores principales: Burdette, Lisa Ann, Leach, Samuel Alexander, Wong, Han Teng, Tullman-Ercek, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302416/
https://www.ncbi.nlm.nih.gov/pubmed/30572895
http://dx.doi.org/10.1186/s12934-018-1041-5