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High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow

BACKGROUND: Cancer is a complex, multiscale dynamical system, with interactions between tumor cells and non-cancerous host systems. Therapies act on this combined cancer-host system, sometimes with unexpected results. Systematic investigation of mechanistic computational models can augment tradition...

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Detalles Bibliográficos
Autores principales: Ozik, Jonathan, Collier, Nicholson, Wozniak, Justin M., Macal, Charles, Cockrell, Chase, Friedman, Samuel H., Ghaffarizadeh, Ahmadreza, Heiland, Randy, An, Gary, Macklin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302449/
https://www.ncbi.nlm.nih.gov/pubmed/30577742
http://dx.doi.org/10.1186/s12859-018-2510-x