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High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow
BACKGROUND: Cancer is a complex, multiscale dynamical system, with interactions between tumor cells and non-cancerous host systems. Therapies act on this combined cancer-host system, sometimes with unexpected results. Systematic investigation of mechanistic computational models can augment tradition...
Autores principales: | Ozik, Jonathan, Collier, Nicholson, Wozniak, Justin M., Macal, Charles, Cockrell, Chase, Friedman, Samuel H., Ghaffarizadeh, Ahmadreza, Heiland, Randy, An, Gary, Macklin, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302449/ https://www.ncbi.nlm.nih.gov/pubmed/30577742 http://dx.doi.org/10.1186/s12859-018-2510-x |
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