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Methylome of human senescent hematopoietic progenitors

Senescence, a state of permanent cell cycle arrest, can be induced by DNA damage. This process, which was initially described in fibroblasts, is now recognized to occur in stem cells. It has been well characterized in cell lines, but there is currently very limited data available on human senescence...

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Detalles Bibliográficos
Autores principales: Capone, Stephen, Colombo, Anthony R., Johnson, Benjamin K., Triche, Tim J., Ramsingh, Giridharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302458/
https://www.ncbi.nlm.nih.gov/pubmed/30598855
http://dx.doi.org/10.1186/s40164-018-0123-8