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Participation in a single-blinded pediatric therapeutic strategy study for juvenile idiopathic arthritis: are parents and patient-participants in equipoise?

BACKGROUND: Genuine uncertainty on superiority of one intervention over the other is called equipoise. Physician-investigators in randomized controlled trials (RCT) need equipoise at least in studies with more than minimal risks. Ideally, this equipoise is also present in patient-participants. In pe...

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Detalles Bibliográficos
Autores principales: Hissink Muller, Petra C. E., Yildiz, Bahar, Allaart, Cornelia F., Brinkman, Danielle M. C., van Rossum, Marion, van Suijlekom-Smit, Lisette W. A., van den Berg, J. Merlijn, ten Cate, Rebecca, de Vries, Martine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302476/
https://www.ncbi.nlm.nih.gov/pubmed/30572875
http://dx.doi.org/10.1186/s12910-018-0336-8