Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs

BACKGROUND: Our understanding of eukaryotic gene regulation is limited by the complexity of protein–DNA interactions that comprise the chromatin landscape and by inefficient methods for characterizing these interactions. We recently introduced CUT&RUN, an antibody-targeted nuclease cleavage meth...

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Detalles Bibliográficos
Autores principales: Janssens, Derek H., Wu, Steven J., Sarthy, Jay F., Meers, Michael P., Myers, Carrie H., Olson, James M., Ahmad, Kami, Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302505/
https://www.ncbi.nlm.nih.gov/pubmed/30577869
http://dx.doi.org/10.1186/s13072-018-0243-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302505/
https://www.ncbi.nlm.nih.gov/pubmed/30577869
http://dx.doi.org/10.1186/s13072-018-0243-8

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