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Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study

BACKGROUND: Venous thromboembolism (VTE) is a relatively rare condition in childhood with treatment mainly based on extrapolation from studies in adults. Therefore, clinical trials of anticoagulation in children require novel approaches to deal with numerous challenges. The EINSTEIN-Jr program ident...

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Detalles Bibliográficos
Autores principales: Lensing, Anthonie W. A., Male, Christoph, Young, Guy, Kubitza, Dagmar, Kenet, Gili, Patricia Massicotte, M., Chan, Anthony, Molinari, Angelo C., Nowak-Goettl, Ulrike, Pap, Ákos F., Adalbo, Ivet, Smith, William T., Mason, Amy, Thelen, Kirstin, Berkowitz, Scott D., Crowther, Mark, Schmidt, Stephan, Price, Victoria, Prins, Martin H., Monagle, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302520/
https://www.ncbi.nlm.nih.gov/pubmed/30598642
http://dx.doi.org/10.1186/s12959-018-0188-y