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Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study
BACKGROUND: Venous thromboembolism (VTE) is a relatively rare condition in childhood with treatment mainly based on extrapolation from studies in adults. Therefore, clinical trials of anticoagulation in children require novel approaches to deal with numerous challenges. The EINSTEIN-Jr program ident...
Autores principales: | Lensing, Anthonie W. A., Male, Christoph, Young, Guy, Kubitza, Dagmar, Kenet, Gili, Patricia Massicotte, M., Chan, Anthony, Molinari, Angelo C., Nowak-Goettl, Ulrike, Pap, Ákos F., Adalbo, Ivet, Smith, William T., Mason, Amy, Thelen, Kirstin, Berkowitz, Scott D., Crowther, Mark, Schmidt, Stephan, Price, Victoria, Prins, Martin H., Monagle, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302520/ https://www.ncbi.nlm.nih.gov/pubmed/30598642 http://dx.doi.org/10.1186/s12959-018-0188-y |
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