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Transcriptomic and fluxomic changes in Streptomyces lividans producing heterologous protein

BACKGROUND: The Gram-positive Streptomyces lividans TK24 is an attractive host for heterologous protein production because of its high capability to secrete proteins—which favors correct folding and facilitates downstream processing—as well as its acceptance of methylated DNA and its low endogeneous...

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Detalles Bibliográficos
Autores principales: Daniels, Wouter, Bouvin, Jeroen, Busche, Tobias, Rückert, Christian, Simoens, Kenneth, Karamanou, Spyridoula, Van Mellaert, Lieve, Friðjónsson, Ólafur H., Nicolai, Bart, Economou, Anastassios, Kalinowski, Jörn, Anné, Jozef, Bernaerts, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302529/
https://www.ncbi.nlm.nih.gov/pubmed/30577858
http://dx.doi.org/10.1186/s12934-018-1040-6