Cargando…

Transcriptomic and fluxomic changes in Streptomyces lividans producing heterologous protein

BACKGROUND: The Gram-positive Streptomyces lividans TK24 is an attractive host for heterologous protein production because of its high capability to secrete proteins—which favors correct folding and facilitates downstream processing—as well as its acceptance of methylated DNA and its low endogeneous...

Descripción completa

Detalles Bibliográficos
Autores principales:	Daniels, Wouter, Bouvin, Jeroen, Busche, Tobias, Rückert, Christian, Simoens, Kenneth, Karamanou, Spyridoula, Van Mellaert, Lieve, Friðjónsson, Ólafur H., Nicolai, Bart, Economou, Anastassios, Kalinowski, Jörn, Anné, Jozef, Bernaerts, Kristel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302529/ https://www.ncbi.nlm.nih.gov/pubmed/30577858 http://dx.doi.org/10.1186/s12934-018-1040-6

Ejemplares similares

Large-scale production of a thermostable Rhodothermus marinus cellulase by heterologous secretion from Streptomyces lividans
por: Hamed, Mohamed Belal, et al.
Publicado: (2017)

Extensive Reannotation of the Genome of the Model Streptomycete Streptomyces lividans TK24 Based on Transcriptome and Proteome Information
por: Droste, Julian, et al.
Publicado: (2021)

Evaluation of Sample Preparation Methods for Inter-Laboratory Metabolomics Investigation of Streptomyces lividans TK24
por: Muhamadali, Howbeer, et al.
Publicado: (2020)

Characterization of Sigma Factor Genes in Streptomyces lividans TK24 Using a Genomic Library-Based Approach for Multiple Gene Deletions
por: Rebets, Yuriy, et al.
Publicado: (2018)

Recombinant production of Streptococcus equisimilis streptokinase by Streptomyces lividans
por: Pimienta, Elsa, et al.
Publicado: (2007)

Monitoring Protein Secretion in Streptomyces Using Fluorescent Proteins
por: Hamed, Mohamed Belal, et al.
Publicado: (2018)

Comprehensive subcellular topologies of polypeptides in Streptomyces
por: Tsolis, Konstantinos C., et al.
Publicado: (2018)

Metabolomics investigation of recombinant mTNFα production in Streptomyces lividans
por: Muhamadali, Howbeer, et al.
Publicado: (2015)

Multi-Omics and Targeted Approaches to Determine the Role of Cellular Proteases in Streptomyces Protein Secretion
por: Busche, Tobias, et al.
Publicado: (2018)

Engineering of Streptomyces lividans for heterologous expression of secondary metabolite gene clusters
por: Ahmed, Yousra, et al.
Publicado: (2020)

Morphology-driven downscaling of Streptomyces lividans to micro-cultivation
por: van Dissel, Dino, et al.
Publicado: (2017)

Regulation of dndB Gene Expression in Streptomyces lividans
por: Dai, Daofeng, et al.
Publicado: (2018)

The Transcription Unit Architecture of Streptomyces lividans TK24
por: Lee, Yongjae, et al.
Publicado: (2019)

Two heterologously expressed Planobispora rosea proteins cooperatively induce Streptomyces lividans thiostrepton uptake and storage from the extracellular medium
por: Giardina, Anna, et al.
Publicado: (2010)

Modification of genetic regulation of a heterologous chitosanase gene in Streptomyces lividans TK24 leads to chitosanase production in the absence of chitosan
por: Dubeau, Marie-Pierre, et al.
Publicado: (2011)

DNA phosphorothioation in Streptomyces lividans: mutational analysis of the dnd locus
por: Xu, Tiegang, et al.
Publicado: (2009)

Extracellular Streptomyces lividans vesicles: composition, biogenesis and antimicrobial activity
por: Schrempf, Hildgund, et al.
Publicado: (2015)

A Reporter System for Fast Quantitative Monitoring of Type 3 Protein Secretion in Enteropathogenic E. coli
por: Barkalita, Luit, et al.
Publicado: (2020)

Comparative genomic hybridizations reveal absence of large Streptomyces coelicolor genomic islands in Streptomyces lividans
por: Jayapal, Karthik P, et al.
Publicado: (2007)

Impact of Phosphate Availability on Membrane Lipid Content of the Model Strains, Streptomyces lividans and Streptomyces coelicolor
por: Lejeune, Clara, et al.
Publicado: (2021)

New approaches to achieve high level enzyme production in Streptomyces lividans
por: Sevillano, Laura, et al.
Publicado: (2016)

Modelling the metabolism of protein secretion through the Tat route in Streptomyces lividans
por: Valverde, José R., et al.
Publicado: (2018)

Dynamics of Pellet Fragmentation and Aggregation in Liquid-Grown Cultures of Streptomyces lividans
por: Zacchetti, Boris, et al.
Publicado: (2018)

Complete Genome Sequences of Streptomyces lividans Bacteriophages Satis and JustBecause
por: Hartigan, Kelly, et al.
Publicado: (2019)

The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in Streptomyces lividans
por: Seghezzi, Nicolas, et al.
Publicado: (2022)

Single Streptomyces lividans K(+) Channels: Functional Asymmetries and Sidedness of Proton Activation
por: Heginbotham, Lise, et al.
Publicado: (1999)

Improving the active expression of transglutaminase in Streptomyces lividans by promoter engineering and codon optimization
por: Liu, Song, et al.
Publicado: (2016)

DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans
por: Dai, Daofeng, et al.
Publicado: (2016)

Microencapsulation extends mycelial viability of Streptomyces lividans 66 and increases enzyme production
por: Zacchetti, Boris, et al.
Publicado: (2018)

Purification and kinetic behavior of glucose isomerase from Streptomyces lividans RSU26
por: Rengasamy, Sathya, et al.
Publicado: (2020)

Fluxome analysis using GC-MS
por: Wittmann, Christoph
Publicado: (2007)

Streptomyces lividans inhibits the proliferation of the fungus Verticillium dahliae on seeds and roots of Arabidopsis thaliana
por: Meschke, Holger, et al.
Publicado: (2010)

A Novel Two-Component System Involved in Secretion Stress Response in Streptomyces lividans
por: Gullón, Sonia, et al.
Publicado: (2012)

Identified members of the Streptomyces lividans AdpA regulon involved in differentiation and secondary metabolism
por: Guyet, Aurélie, et al.
Publicado: (2014)

Engineered Streptomyces lividans Strains for Optimal Identification and Expression of Cryptic Biosynthetic Gene Clusters
por: Peng, Qinying, et al.
Publicado: (2018)

Dynamic metabolic modelling of overproduced protein secretion in Streptomyces lividans using adaptive DFBA
por: Valverde, Jósé R., et al.
Publicado: (2019)

Intracellular Phage Tail-Like Nanostructures Affect Susceptibility of Streptomyces lividans to Osmotic Stress
por: Nagakubo, Toshiki, et al.
Publicado: (2023)

Cloning of ε-poly-L-lysine (ε-PL) synthetase gene from a newly isolated ε-PL-producing Streptomyces albulus NK660 and its heterologous expression in Streptomyces lividans
por: Geng, Weitao, et al.
Publicado: (2014)

High-Level Overproduction of Thermobifida Enzyme in Streptomyces lividans Using a Novel Expression Vector
por: Li, Jun-Xia, et al.
Publicado: (2013)

Germination and Growth Analysis of Streptomyces lividans at the Single-Cell Level Under Varying Medium Compositions
por: Koepff, Joachim, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_k8va9moosp7lgasgmu83bbnrgi