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Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential

We characterized 55 influenza A(H9N2) viruses isolated in Pakistan during 2014–2016 and found that the hemagglutinin gene is of the G1 lineage and that internal genes have differentiated into a variety of novel genotypes. Some isolates had up to 4-fold reduction in hemagglutination inhibition titers...

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Detalles Bibliográficos
Autores principales: Sealy, Joshua E., Yaqub, Tahir, Peacock, Thomas P., Chang, Pengxiang, Ermetal, Burcu, Clements, Anabel, Sadeyen, Jean-Remy, Mehboob, Arslan, Shelton, Holly, Bryant, Juliet E., Daniels, Rod S., McCauley, John W., Iqbal, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302589/
https://www.ncbi.nlm.nih.gov/pubmed/30561311
http://dx.doi.org/10.3201/eid2501.180616