Improved protein production and codon optimization analyses in Escherichia coli by bicistronic design

Different codon optimization algorithms are available that aim at improving protein production by optimizing translation elongation. In these algorithms, it is generally not considered how the altered protein coding sequence will affect the secondary structure of the corresponding RNA transcript, pa...

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Detalles Bibliográficos
Autores principales: Nieuwkoop, Thijs, Claassens, Nico J., van der Oost, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302717/
https://www.ncbi.nlm.nih.gov/pubmed/30484964
http://dx.doi.org/10.1111/1751-7915.13332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302717/
https://www.ncbi.nlm.nih.gov/pubmed/30484964
http://dx.doi.org/10.1111/1751-7915.13332

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