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PD-L1 monoclonal antibody-conjugated nanoparticles enhance drug delivery level and chemotherapy efficacy in gastric cancer cells

BACKGROUND: Docetaxel (DOC) is widely used as a chemotherapy drug for various tumors, including gastric cancer (GC), but the clinical application of DOC has been limited due to the hydrophobicity of the drug. We aimed to formulate a multifunctional nanoparticle (NP) system to reduce the side effects...

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Detalles Bibliográficos
Autores principales: Xu, Shijie, Cui, Fangbo, Huang, Dafu, Zhang, Dinghu, Zhu, Anqing, Sun, Xia, Cao, Yiming, Ding, Sheng, Wang, Yao, Gao, Eryun, Zhang, Fenglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302817/
https://www.ncbi.nlm.nih.gov/pubmed/30587982
http://dx.doi.org/10.2147/IJN.S175340